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Key Coordination Steps Before Starting Semaglutide With HRT Inform your prescribing clinician about all current medications, including the specific HRT formulation, dose, and route (oral, transdermal, or injection)

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Garvey WT, Batterham RL, Bhatta M (2022) Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial

They also say that muscle loss triggered by the drug means someone who uses it cannot return to their old diet because it will lead to weight gain